Three serums, three mechanisms, three price points. Here's how to pick the one your skin actually needs.
What each one is
Exosomes — donor-derived signaling vesicles loaded with growth factors, peptides, and mRNA. The newest of the three. Most aggressive collagen response.
PRP (Platelet-Rich Plasma) — your own blood, centrifuged to isolate platelets and growth factors. Autologous — zero allergy risk. The original “Vampire Facial” serum.
PDRN (Polydeoxyribonucleotide) — salmon DNA fragments. Strong anti-inflammatory effect. Excellent for sensitive skin or rosacea-prone patients.
What each one does best
Exosomes — fastest collagen response, best for serious scar work, most rapid visible results. Best fit: deep acne scars, mature skin needing visible rejuvenation in fewer sessions.
PRP — strong general rejuvenation, excellent healing acceleration, autologous (your own body). Best fit: patients wanting natural ingredients, mid-tier scar work, anti-aging without donor materials.
PDRN — anti-inflammatory powerhouse, soothes sensitive or reactive skin, great for redness and rosacea overlap. Best fit: rosacea-prone skin, sensitive Fitzpatrick I-III, post-laser healing acceleration.
Cost — direct comparison
PDRN typically lands between PRP and Exosomes in price. PRP is the lowest-cost add-on (no external biologic). Exosomes are the premium option — typically 1.5x to 2x the PRP price. Exact pricing varies — see our price list for current numbers.
Sessions and combinations
For acne scarring, we often start with Exosomes for the first 2 to 3 sessions to drive faster initial response, then maintain with PRP. For sensitive or rosacea patients, PDRN throughout. For rejuvenation in patients who want their own biologics only, PRP throughout.
What to pick
Consultation is the answer. We assess your skin type, your concerns, and your budget — and design a protocol that fits all three. Sometimes the right answer is a mix across the course.
Book your free consultation
Speak with a licensed Bar Beauty injector or laser tech. We’ll review your goals, walk through options, and give you a clear plan — zero pressure.
46 Fort York Blvd, Toronto · 416-923-1200 · Open 7 days
Written by the Bar Beauty Medical clinical team. We’re a medical aesthetics clinic at 46 Fort York Blvd, Toronto. All treatments are performed by licensed nurses, doctors, or laser technicians. Information here is general; for advice specific to your skin and goals, book a free consultation.