All four neurotoxins use botulinum toxin type A to soften expression lines, but they differ in onset speed, spread, and longevity. Choose Dysport for faster onset and wider spread on the forehead. Choose Xeomin if you have developed resistance to other neurotoxins. Choose Botox for the most predictable, well-studied result. Choose Nuceiva for a Canadian-priced alternative with Botox-equivalent dosing.
Last updated: May 12, 2026.
Quick Comparison Table
| Brand | Onset | Peak Effect | Duration | Conversion to Botox | Starting Price (Toronto) |
|---|---|---|---|---|---|
| Botox (onabotulinumtoxinA) | 3-5 days | 10-14 days | 3-4 months | 1:1 | $10-$14/unit |
| Dysport (abobotulinumtoxinA) | 1-3 days | 7-10 days | 3-4 months | 1:2.5 | $5-$6/unit |
| Xeomin (incobotulinumtoxinA) | 3-5 days | 10-14 days | 3-4 months | 1:1 | $11-$13/unit |
| Nuceiva (prabotulinumtoxinA) | 3-5 days | 7-14 days | 3-4 months | 1:1 | $9-$11/unit |
What is Botox?
The original brand of botulinum toxin type A, remains the gold standard. Includes a complexing protein that surrounds the active toxin. Decades of clinical data and predictable dosing make it the most commonly requested neurotoxin in Toronto.
What is Dysport?
Smaller molecules than Botox, different complexing protein. Diffuses more, advantage for forehead, disadvantage for precise areas like mouth corners. Onset typically 1-2 days faster.
What is Xeomin?
“Naked” toxin with no complexing proteins. Absence of accessory proteins may reduce chance of developing neutralizing antibodies. Used for patients who stopped responding to Botox.
What is Nuceiva?
Newest neurotoxin approved in Canada. Dosed 1:1 with Botox, comparable results in glabellar lines. Priced more affordably.
When to Choose Each
Botox for fine-tuned areas (lip flip, masseters, brow lifts). Dysport for full forehead treatments when wedding/event is 2 weeks away. Xeomin if Botox results weakened despite consistent dosing. Nuceiva for budget-conscious forehead/glabella maintenance.
Cost Comparison in Toronto
Botox: $10-$14/unit (Bar Beauty $10 flat). Xeomin: $11-$13/unit. Nuceiva: $9-$11/unit. Dysport: $5-$6/unit (but units are 2.5x smaller, so total cost per area is comparable).
Can I Combine Them?
Do not mix two neurotoxins in same session. You can switch brands between sessions. Some patients alternate yearly. Switch to Xeomin if you notice diminishing returns.
FAQ
Which lasts longest?
All four typically last 3-4 months. Patient metabolism, dose, and muscle strength influence duration more than brand.
Which kicks in fastest?
Dysport, often within 24-72 hours.
Can I build immunity?
Rarely. Xeomin purified formulation is preferred for those concerned about antibody formation.
Is one safer than another?
All four are Health Canada approved with similar safety profiles when administered by trained medical injector.
Why is Dysport priced lower per unit?
Dysport units are smaller. Total cost per area is similar to Botox.
Talk to Bar Beauty Medical Toronto
Bar Beauty Medical stocks all four major neurotoxins at the CityPlace Fort York clinic, so your injector can recommend the best fit based on muscle pattern and history. Visit 46 Fort York Blvd to map out a neurotoxin plan.